I have a problem on the T3 Plus with Ubuntu / 4.4.49-s5p6818

I'm trying to disable and reenable a USB hub with

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echo "2-" | sudo tee /sys/bus/usb/drivers/usb/unbind
echo "2-" | sudo tee /sys/bus/usb/drivers/usb/bind

but it always fails with:

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$ dmesg | tail -n 1
[ 2012.628000] usb 2- can't set config #1, error -22

Doesn't matter what level of USB device I try this at - even at the root hub

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echo "usb2" | sudo tee /sys/bus/usb/drivers/usb/unbind
always the same error. Only a reboot will fix it. Can anyone else reproduce this and/or suggest a fix? Thanks.